Museum of Yebisu Beer: Tokyo's Only Beer Museum
There is a tour (500 yen) of the brewing process given in Japanese. I didn't take the tour, though I might try in the future with a Japanese friend. A store is located across from the gallery as well as a tasting bar - beers can be purchased with Yebisu coins - one coin (400 yen) gives you one beer; food costs one or two coins.
The museum is open Tuesdays through Sundays 11AM-7PM. The museum itself is free and is located in Ebisu Garden Place, about five minutes walk from Ebisu Station on the JR and Hibiya lines.